USC Trojans vs Indiana Hoosiers Prediction & Odds – November 14, 2026

USC visits Indiana in a meeting of teams with identical scoring averages but different defensive profiles. The Trojans bring the stronger passing output; the Hoosiers allow fewer points and yards per game.

Game details and odds

Saturday, November 14, 2026 at 3:30 pm EST · Memorial Stadium (Bloomington, IN)

Total: 50.5 — over -108, under -112.

Draft Kings odds checked November 12, 2026 15:00 UTC. Odds subject to change.

USC’s passing production meets Indiana’s defense

USC averages 32.4 points and 423.8 yards per game, with 294.4 yards coming through the air. Jayden Maiava has thrown for 2,524 yards and 20 touchdowns, giving the Trojans a clear route to moving the ball. Their defense, however, allows 24.2 points per game.

The Trojans’ completed games show both the appeal and the risk of leaning on their offense. They beat Ohio State 30-18 at home and won 31-23 at Penn State, results that show they can produce against opponents in different settings. But their trip to Wisconsin ended in a 24-7 loss, a sharp contrast with those wins. USC also edged Washington 25-21 and lost 41-27 to Oregon at home. The spread of scores suggests USC can win close contests, but its scoring has not been equally reliable from game to game.

Indiana’s defense anchors a balanced attack

Indiana also averages 32.4 points per game, though its 186.2 rushing yards per game give its offense a different shape. Turbo Richard has 745 rushing yards, while Josh Hoover has thrown 19 touchdowns. The Hoosiers allow 12.4 points and 259.2 yards per game, both lower figures than USC’s.

Indiana’s recent completed games have been tighter than its 47-15 win at Rutgers might suggest. The Hoosiers beat Minnesota 23-16 at home, won 13-6 at Michigan and prevailed 20-17 at Nebraska. They also lost 19-15 to Ohio State at home, showing that keeping an opponent’s score down does not guarantee a win when their own offense is limited. Those results give Indiana a credible path through lower-scoring play, but they also leave room for a close finish if the Hoosiers struggle to turn possessions into points.

Injury news

USC Trojans: No player statuses returned in the latest check..

Indiana Hoosiers: No player statuses returned in the latest check..

Availability checked November 12, 2026 15:00 UTC. Reported statuses may change; final lineups are not confirmed here.

BTB Betting Pick

Winner pick: Indiana Hoosiers.

Indiana’s lower points and yards allowed per game provide the clearest edge, and its rushing production offers another way to sustain offense. USC’s passing output makes a Hoosiers win far from certain.

Original winner pick recorded November 12, 2026 08:00 UTC. Subsequent updates retain that selection.