Pittsburgh Steelers vs Detroit Lions Betting Pick & Prediction for 12/21
This article was published on Dec 17, 2025. Today’s picks NFL picks

The Pittsburgh Steelers are set to play the Detroit Lions in Week 16 of the 2025 season. This game will take place at Ford Field in Detroit. Fans can watch the action live on CBS at 4:25 PM on December 21.
Both teams have identical records of 8-6 this season. The Steelers have a road record of 3-3, while the Lions have a strong home record of 5-2. The weather outside is expected to be very cold, but it won’t affect the game inside the dome.
Pittsburgh Steelers Team Preview
The Pittsburgh Steelers have been on a roll recently, winning three of their last four games. They secured victories over the Miami Dolphins, Baltimore Ravens, and Cincinnati Bengals. Their lone loss came against the Buffalo Bills, where they struggled both offensively and defensively.
Aaron Rodgers leads the Steelers’ offense with 2,594 passing yards and 22 touchdowns. DK Metcalf has been his go-to receiver, recording 808 yards and six touchdowns. On the ground, Jaylen Warren and Kenneth Gainwell have been effective, combining for over 1,100 rushing yards this season.
Defensively, the Steelers rank high in interceptions and fumbles recovered. Jalen Ramsey and Cameron Heyward have been key players on this side of the ball. The team faces injury challenges, with several players on the injured reserve list, but they continue to perform well overall.
Steelers vs Lions Game Day Info
- Sport: NFL
- Teams: Pittsburgh Steelers vs. Detroit Lions
- Venue: Ford Field in Detroit, MI
- Date: Sunday, December 21, 2025
- Betting Odds: Steelers Moneyline +264, Lions Moneyline -329, Steelers Spread +7.0 (-110), Lions Spread -7.0 (-110), Total Over 52.0 (-109), Total Under 52.0 (-110)
Detroit Lions Team Preview
The Detroit Lions have been strong on offense this season. In their recent game against the Los Angeles Rams, Jared Goff threw for 338 yards and three touchdowns. Amon-Ra St. Brown had a standout performance with 164 receiving yards and two touchdowns.
The Lions faced the Dallas Cowboys at home and won 44-30. Jahmyr Gibbs led the rushing attack with three touchdowns. Jared Goff continued his solid play, adding another 309 passing yards and one touchdown.
Injuries have affected the Lions’ depth, especially on defense. Key players like Sam LaPorta and Brock Wright are currently out. Despite these setbacks, the team has shown resilience, especially in their offensive performances.
BTB Betting Pick
The Lions are favored by 7 points against the Steelers. With the Lions having the top-ranked offense, scoring 564 points this season, they are likely to cover the spread. The projected score is Lions 31, Steelers 20, suggesting the Lions will win by more than 7 points.
The over/under line is set at 52. The Lions’ offense is strong, but both teams have solid defenses. The projected total score is 51, so the recommendation is to take the under.