College Football Playoff First Round Game: Tulane Green Wave vs Ole Miss Rebels Betting Pick & Prediction for 12/20

The 2025 College Football Playoff First Round Game is set for an exciting showdown. Tulane Green Wave will take on Ole Miss Rebels at Vaught-Hemingway Stadium. This game is scheduled for Saturday, December 20, 2025, at 3:30 PM and will air on TNT.

Tulane comes into this game ranked 17th in the AP Poll and 18th in the Coaches Poll. They hold an 11-2 record, with an impressive 8-1 in conference play. Ole Miss, ranked 6th in both polls, boasts an 11-1 record. They have dominated at home with an 8-0 record this season.

Tulane Team Preview

Tulane Green Wave has been strong in their recent games. They won against North Texas 34-21, with a solid rushing game of 202 yards. The team also had no interceptions in that game, showing care with the ball.

The Green Wave dominated Charlotte 49ers with a 27-0 win. They had 312 passing yards and held the 49ers to only seven first downs. This game highlighted their defensive strength, not allowing any points.

Jake Retzlaff, the quarterback, has played in 13 games with 2862 passing yards. However, Tulane is facing some injury challenges. Key players like Maurice Turner and Brendan Sullivan are listed as questionable, which could impact their performance.

College Football Playoff First Round Game: Tulane vs Ole Miss Game Day Info

• Sport: College Football
• Teams: Tulane Green Wave vs. Ole Miss Rebels
• Venue: Vaught-Hemingway Stadium in Oxford, MS
• Date: Saturday, December 20, 2025
• Betting Odds: Tulane +604, Ole Miss -924, Spread Tulane +17.5 (-112), Spread Ole Miss -17.5 (-109), Total Over 56.5 (-112), Total Under 56.5 (-109)

Ole Miss Team Preview

Ole Miss Rebels have shown strong performances in their recent games. They won against Mississippi State Bulldogs 38-19 on November 28th. In that game, Ole Miss had 359 passing yards and 187 rushing yards.

Earlier in the season, they won against Florida Gators 34-24 at home. In this game, Ole Miss had 301 passing yards and 241 rushing yards. They also had more first downs than Florida with 27 to 14.

Trinidad Chambliss is a key player for Ole Miss, leading the team with 3016 passing yards. Kewan Lacy is the top running back with 1279 rushing yards. Ole Miss’s defense also contributes with 25 sacks and 7 interceptions this season.

BTB Betting Pick

For the spread pick, Ole Miss is favored by 17.5 points. With their strong offense ranked 13th in points for, and Tulane’s defense ranked 103rd in points against, Ole Miss is likely to cover the spread. The projected score is Ole Miss 38, Tulane 17, suggesting Ole Miss covers the -17.5 spread.

For the over/under pick, the total is set at 56.5 points. Ole Miss has a high-scoring offense, but Tulane’s lower offensive output and Ole Miss’s decent defense suggest a lower total. The projected total score is 55, making the under 56.5 a reasonable choice.