Buffalo Bills vs New England Patriots Betting Pick & Prediction for 12/14

NFL Game preview

The Buffalo Bills will head to Gillette Stadium to take on the New England Patriots in Week 15 of the 2025 season. The game is set for Sunday, December 14, at 1:00 PM and will be broadcast on CBS. Weather conditions are expected to be very cold with overcast clouds and a light breeze.

The Bills, led by head coach Sean McDermott, have a season record of 9-4-0. They are facing a strong Patriots team with an 11-2-0 record under head coach Mike Vrabel. Both teams are in the AFC East division, making this matchup an important one for divisional standings.

Buffalo Bills Team Preview

The Buffalo Bills have had a solid season so far. They recently defeated the Cincinnati Bengals 39-34 at home. Josh Allen led the offense with 251 passing yards and three touchdowns.

In their recent away game, the Bills secured a 26-7 win against the Pittsburgh Steelers. James Cook stood out with 144 rushing yards. Their defense held the Steelers to just ten first downs.

Despite a loss to the Houston Texans, the Bills’ rushing game showed strength. James Cook managed 116 rushing yards and a touchdown. Injuries remain a concern for the team with several key players on the injured reserve list.

Bills vs Patriots Game Day Info

  • Sport: NFL
  • Teams: Buffalo Bills vs. New England Patriots
  • Venue: Gillette Stadium in Foxborough, MA USA
  • Date: Sunday, December 14, 2025
  • Betting Odds: Bills Moneyline -115, Patriots Moneyline -104, Bills Spread -1.0 (-106), Patriots Spread +1.0 (-112), Total Over/Under 49.5 (-110)

New England Patriots Team Preview

The New England Patriots have been strong this season. They won their last game against the New York Giants, 33-15. Quarterback Drake Maye threw for 282 yards and two touchdowns, leading the offense at Gillette Stadium.

Drake Maye has been impressive all season. He ranks first in the league with 3,412 passing yards. Maye has thrown 23 touchdowns and only six interceptions in 13 games.

TreVeyon Henderson is another key player for the Patriots. He has rushed for 625 yards and scored five rushing touchdowns. The team’s defense is also performing well, with Harold Landry III recording a sack in the win against the Giants.

BTB Betting Pick

The Bills are favored by 1 point over the Patriots. The Bills have a strong offense, ranking 2nd in scoring, while the Patriots are ranked 28th. With the Bills’ ability to score and the Patriots’ struggles, the Bills are likely to cover the spread. The projected score is Bills 28, Patriots 20.

The total for the game is set at 49.5 points. The Bills have a solid defense, ranked 11th in opponent scoring, while the Patriots’ offense is ranked 28th in scoring. This may lead to a lower-scoring game. The projected total is 48 points, suggesting the under is a good pick.