Indianapolis Colts vs Kansas City Chiefs Betting Pick & Prediction for 11/23

The Indianapolis Colts are set to play against the Kansas City Chiefs in Week 12 of the 2025 NFL season. The game will take place at Arrowhead Stadium in Kansas City on Sunday, November 23, at 1:00 PM. The weather forecast predicts a cool day with clear skies and a light breeze, making for good playing conditions.

The Colts, led by head coach Shane Steichen, have an impressive record of 8-2-0 this season. They have been strong at home with a perfect 6-0-0 record, but their road record stands at 2-2-0. The Chiefs, under head coach Andy Reid, hold a 5-5-0 record. They have been more successful at home with a 4-1-0 record. The game will be broadcast on CBS.

Indianapolis Colts Team Preview

The Indianapolis Colts have had a mixed season so far. They have shown strong performances with wins against teams like the Tennessee Titans and Los Angeles Chargers. However, they faced a setback in their recent game against the Pittsburgh Steelers, losing 27-20.

Quarterback Daniel Jones has been a key player for the Colts this season. He ranks third in the league for passing yards with 2,659 yards. Despite his efforts, turnovers have been an issue, as seen in the game against the Steelers where he threw three interceptions.

The Colts’ running game is led by Jonathan Taylor, who ranks first in the league with 1,139 rushing yards. He has contributed 15 rushing touchdowns this season, making him a crucial part of the offense. The team will need to rely on his performance, especially with several players currently on the injured reserve list.

Colts vs Chiefs Game Day Info

• Sport: NFL
• Teams: Indianapolis Colts vs. Kansas City Chiefs
• Venue: Arrowhead Stadium in Kansas City, MO
• Date: Sunday, November 23, 2025
• Betting Odds: Colts Moneyline +150, Chiefs Moneyline -179, Colts Spread +3.5 (-119), Chiefs Spread -3.5 (-101), Total Over 50.5 (-110), Total Under 50.5 (-111)

Kansas City Chiefs Team Preview

The Kansas City Chiefs have shown mixed results in their recent games. They had a narrow loss to the Denver Broncos, 22-19, despite gaining more first downs. Patrick Mahomes threw for 276 yards, but an interception proved costly.

In their previous outing against the Buffalo Bills, the Chiefs also fell short, losing 28-21. Their rushing game struggled with only 79 yards. Rashee Rice stood out with 80 receiving yards, but the team couldn’t secure the win.

The Chiefs had better outcomes at home, beating the Washington Commanders 28-7 and the Las Vegas Raiders 31-0. Mahomes was key, throwing for multiple touchdowns in both games. The defense held strong, keeping the Raiders scoreless and limiting the Commanders to just one touchdown.

BTB Betting Pick

The spread for the game is Chiefs -3.5. The Chiefs have a strong defense, ranked 4th in opponent scoring, while the Colts rank 23rd in the same category. This defensive edge gives the Chiefs a projected advantage. The pick is for the Chiefs to cover the -3.5 spread.

The total for the game is set at 50.5. The Colts’ defense has allowed a high number of points, while the Chiefs have a top-10 offense. This suggests a high-scoring game. The recommendation is to take the over 50.5 total.