Notre Dame Fighting Irish vs Pittsburgh Panthers Betting Pick & Prediction for 11/15

College Football Preview

In Week 12 of the 2025 college football season, the Notre Dame Fighting Irish travel to face the Pittsburgh Panthers. The game takes place at Acrisure Stadium in Pittsburgh, PA, on Saturday, November 15, 2025, with kickoff scheduled for 12:00 PM. Fans can tune in to watch the game live on ABC. Notre Dame, ranked ninth in both the AP and Coaches Polls, enters the game with a 7-2 record. The Pittsburgh Panthers, ranked 23rd, also hold a 7-2 record. Both teams will look to improve their standings as they compete on an outdoor field in front of a home crowd.

Notre Dame Team Preview

Notre Dame has shown strong performance in recent games. They have won their last five games, with the most recent victory against Navy, 49-10. The team had 23 first downs, 253 passing yards, and 252 rushing yards in that game.

The Fighting Irish have been consistent on both sides of the ball. Their offense has scored 348 points this season, ranking 12th. On defense, they have allowed 169 points, placing them 65th overall.

Key players for Notre Dame include CJ Carr, who has thrown for 2,275 yards and 19 touchdowns. Jeremiyah Love leads the rushing attack with 988 yards and 13 touchdowns. Jordan Faison is the top receiver, with 545 yards and three touchdowns.

Notre Dame vs Pittsburgh Game Day Info

  • Sport: NCAA Football
  • Teams: Notre Dame Fighting Irish vs. Pittsburgh Panthers
  • Venue: Acrisure Stadium in Pittsburgh, PA
  • Date: Saturday, November 15, 2025
  • Betting Odds: Notre Dame -435, Pittsburgh +334

Pittsburgh Team Preview

The Pittsburgh Panthers have shown strong offense in recent games. They won against Stanford Cardinal with a score of 35-20. In that game, the Panthers achieved 25 first downs and 304 passing yards. Their defense also contributed with 3 interceptions.

The Panthers delivered a high-scoring game against North Carolina State Wolfpack. They won 53-34 at home in Acrisure Stadium. With 29 first downs and 423 passing yards, the offense led the way. Despite one interception, they kept control of the game.

In the game against Syracuse Orange, the Panthers secured a 30-13 win. The defense was effective, grabbing 3 interceptions. The Panthers managed 16 first downs and had a balanced attack with 143 passing yards and 122 rushing yards.

BTB Betting Pick

The spread for the game is Notre Dame -11.5. Notre Dame has scored 348 points this season, ranking 12th, while Pittsburgh has allowed 196 points, ranking 80th. With Notre Dame’s strong offense and Pittsburgh’s weaker defense, Notre Dame is likely to cover the spread. The projected score is Notre Dame 35, Pittsburgh 21.

The total for the game is set at 55.5 points. Notre Dame’s defense ranks 65th, allowing 169 points, and Pittsburgh’s offense ranks 10th with 357 points. Given these stats, the game may see a combined score that exceeds the total. The projected total is 56 points, suggesting a pick on the over.