New Orleans Pelicans vs Memphis Grizzlies Betting Pick & Prediction for 10/22

The NBA regular season is set to begin with the New Orleans Pelicans facing the Memphis Grizzlies at FedExForum. Both teams are looking to start their season with a win. The game will take place on Wednesday, October 22, 2025, at 8:00 PM and will be broadcasted on FDSS.

The Pelicans, led by head coach Willie Green, are coming off a winless preseason with a 0-2 record. On the other hand, the Grizzlies, coached by Tuomas Iisalo, secured one win in their preseason, ending with a 1-4 record. Both teams are in the Western Conference and part of the Southwest Division, adding some rivalry to this early-season game.

Pelicans vs Grizzlies Game Day Info

• Sport: NBA
• Teams: New Orleans Pelicans vs. Memphis Grizzlies
• Venue: FedExForum
• Date: Wednesday, October 22, 2025
• Betting Odds: Grizzlies favored, Pelicans +155, Grizzlies -184

New Orleans Pelicans Team Preview

The New Orleans Pelicans are coming off a close preseason game against the Orlando Magic, where they lost 132-125. Zion Williamson led the team with 18 points, showing great accuracy with a field goal percentage of 81.8%. Trey Murphy III also contributed with 18 points and 7 rebounds in the game.

In their previous preseason game, the Pelicans faced the Houston Rockets at home. They lost by just two points, 130-128. Jeremiah Fears stood out with 20 points and 6 rebounds, while Zion Williamson added 13 points and 4 assists.

The Pelicans have some players dealing with injuries. Kevon Looney is out with a knee issue, and Dejounte Murray is recovering from an Achilles injury. Karlo Matković is doubtful due to an elbow injury, which might impact the team’s depth in upcoming games.

Memphis Grizzlies Team Preview

The Memphis Grizzlies recently played against the Miami Heat and won by 16 points with a final score of 141-125. Key players like Jaylen Wells contributed significantly, scoring 21 points in just 21 minutes. The Grizzlies had an impressive field goal percentage of 52.9% during this game.

In their game against the Charlotte Hornets, the Grizzlies lost by 29 points, with a final score of 116-145. Javon Small stood out, scoring 18 points and providing 8 assists. The team’s field goal percentage in this game was lower at 42.7%.

The Grizzlies faced the Atlanta Hawks at home and lost by 6 points, with a score of 116-122. Santi Aldama made a notable impact with 10 points and 10 rebounds. Despite the loss, Jaylen Wells managed to score 15 points in 24 minutes.

BTB Betting Pick

For the spread pick, take the Grizzlies at -4.5. The Grizzlies are the favorites with a moneyline of -184, suggesting confidence in their ability to cover the spread. With no available stats, the odds indicate the Grizzlies have the edge.

For the over/under, consider the under at 236.5. Without specific scoring stats, this total seems high. The odds for the under at -109 suggest a closer game with fewer points, making the under a reasonable choice.