Boston College Eagles vs Louisville Cardinals Betting Pick & Prediction for 10/25

This article was published on Oct 21, 2025. Today’s picks College Football picks

College Football Preview

Week 9 of the 2025 college football season brings us a game between the Boston College Eagles and the Louisville Cardinals. The game will take place at L&N Federal Credit Union Stadium in Louisville, KY. Fans can tune in on ACCN at 7:30 PM to watch the action under the night sky.

Boston College enters the game with a record of 1-6. They have struggled in conference play, holding a 0-4 record. On the other hand, Louisville is having a strong season with a 5-1 record and is ranked #19 in the AP Poll. The Cardinals have been solid at home, winning three out of four games in their stadium.

Boston College Team Preview

Boston College Eagles have struggled in recent games. They lost 38-23 against Connecticut Huskies in Week 8. Their passing game was limited to 204 yards, while their opponents gained 362 yards through the air.

Their defense has allowed a high number of points this season. They rank 123rd in points against, with 237 points allowed. Despite this, they have shown strength in interceptions and fumbles recovered, ranking 5th and 8th, respectively.

On offense, Dylan Lonergan leads as their top quarterback. He has thrown for 1,394 yards and 9 touchdowns in 6 games. Turbo Richard is their leading rusher with 431 yards and 5 touchdowns over 7 games.

Boston College vs Louisville Game Day Info

  • Sport: NCAA Football
  • Teams: Boston College Eagles vs. Louisville Cardinals
  • Venue: L&N Federal Credit Union Stadium, Louisville, KY
  • Date: Saturday, October 25, 2025
  • Betting Odds: Boston College +1390, Louisville -3389

Louisville Team Preview

The Louisville Cardinals have shown a strong performance in recent games. They won against the Miami Hurricanes with a score of 24-21. The team secured more first downs and interceptions than Miami, which helped them to victory.

In their game against the Virginia Cavaliers, the Cardinals fell short by a score of 30-27. Despite having more first downs and passing yards, turnovers played a role in the loss. The team fumbled three times, which hindered their ability to maintain control.

Quarterback Miller Moss has been a key player for the Cardinals. He has 1,606 passing yards over six games this season. The team also faces several injuries, with notable players like Stanquan Clark out for the season.

BTB Betting Pick

For the spread, take Boston College to cover +25.5 points. Louisville has scored 204 points this season, ranking 45th, while Boston College is not far behind with 190 points at 51st. Although Louisville’s defense is stronger, Boston College can stay within the spread.

For the total, choose the under 55.5 points. Boston College’s defense has allowed 237 points, ranking 123rd, while Louisville has allowed 126 points, ranking 64th. The projected score is Louisville 34, Boston College 17, which totals 51 points, under the set line.