UCLA Bruins vs Indiana Hoosiers Betting Pick & Prediction for 10/25
This article was published on Oct 21, 2025. Today’s picks College Football picks

The UCLA Bruins will travel to face the Indiana Hoosiers in Week 9 of the 2025 regular season. The game is set for Saturday, October 25, 2025, at Memorial Stadium in Bloomington, Indiana. Fans can catch the action on FOX at 12:00 PM.
UCLA enters the game with a 3-4 record, including a 3-1 mark in the Big Ten Conference. Meanwhile, Indiana holds a perfect 7-0 record and is ranked #2 in both the AP and Coaches Polls. The Hoosiers have been dominant at home, winning all five of their games at Memorial Stadium this season.
UCLA Team Preview
The UCLA Bruins have shown strong performances in recent games. They secured a 20-17 win over Maryland with 221 passing yards and 193 rushing yards. In their previous game, they won against Michigan State 38-13, highlighting their strength in rushing with 238 yards.
Nico Iamaleava, the Bruins’ quarterback, has been consistent. He has thrown for 1,355 yards and 10 touchdowns over seven games. Jalen Berger and Jaivian Thomas have contributed to the rushing game with over 230 yards each.
The Bruins face injury challenges with several players uncertain or out for the season. Key players like Jaylan Jeffers and K.D. Arnold are out for the rest of the season. Despite these setbacks, UCLA aims to continue their winning streak.
UCLA vs Indiana Game Day Info
- Sport: NCAA Football
- Teams: UCLA Bruins vs. Indiana Hoosiers
- Venue: Memorial Stadium, Bloomington, IN
- Date: Saturday, October 25, 2025
- Betting Odds: UCLA +1413, Indiana -3846
Indiana Team Preview
The Indiana Hoosiers have been performing well in recent games. They scored a big win against Michigan State, finishing 38-13. The Hoosiers gained 332 passing yards and 133 rushing yards in that game.
Indiana’s offense has been strong this season. They have a total of 307 points and rank 3rd in points for the season. The team has also gained 1899 passing yards and 1652 rushing yards so far.
Fernando Mendoza has been a key player for the Hoosiers. He has 1755 passing yards and 21 touchdowns in seven games. Despite some injuries, the team continues to perform well on the field.
BTB Betting Pick
For the spread, Indiana is favored by 25.5 points. Indiana has a high-scoring offense, ranking 3rd in points for this season. UCLA’s defense ranks 104th in points against, which may struggle against Indiana’s strong attack. The recommendation is to pick Indiana to cover the -25.5 spread.
The total for the game is set at 54.5 points. Indiana has scored 307 points this season, while UCLA has allowed 192 points. Given Indiana’s offensive capabilities and UCLA’s defensive struggles, the projected score is Indiana 42, UCLA 17. The recommendation is to take the over 54.5 total.