Iowa State Cyclones vs Cincinnati Bearcats Betting Pick & Prediction for 10/4

This article was published on Oct 2, 2025. Today’s picks College Football picks

Latest prediction for this matchup: Cincinnati Bearcats vs Iowa State Cyclones, Nov 14

College Football Preview

This Saturday, the Iowa State Cyclones visit the Cincinnati Bearcats in Week 6 of the 2025 regular season. The game will take place at Nippert Stadium in Cincinnati, Ohio. Kickoff is scheduled for 12:00 PM, and fans can watch the game on ESPN2.

Iowa State enters the game with a perfect 5-0 record. They are ranked #14 in the AP poll and #12 in the Coaches Poll. The Cyclones are strong on the road, holding a 1-0 away record this season. On the other side, Cincinnati has a 3-1 record with a solid 2-1 at home. Both teams are part of the Big 12 Conference.

Iowa State Team Preview

The Iowa State Cyclones have been performing well this season. They won their last game against the Arizona Wildcats with a score of 39-14. Rocco Becht, their top quarterback, has played in all five games, throwing for 1,103 yards and seven touchdowns.

Carson Hansen leads the team in rushing with 315 yards over five games. He has scored two rushing touchdowns. Abu Sama III is another key running back with 208 rushing yards and two touchdowns.

The Cyclones have a solid defense, ranking 7th in interceptions with six so far. They also have recovered two fumbles this season. Injuries are a concern, with several players out, including wide receiver Daniel Jackson and kicker Kyle Konrardy.

Iowa State vs Cincinnati Game Day Info

  • Sport: NCAA Football
  • Teams: Iowa State Cyclones vs. Cincinnati Bearcats
  • Venue: Nippert Stadium in Cincinnati, OH
  • Date: Saturday, October 4, 2025
  • Betting Odds: Iowa State Moneyline +104, Cincinnati Moneyline -123

Cincinnati Team Preview

The Cincinnati Bearcats have shown strong performances in recent games. They defeated Kansas Jayhawks 37-34 on September 27th. In that game, the Bearcats had 29 first downs and gained 215 rushing yards.

Earlier in the season, they won against Northwestern State Demons with a 70-0 score. In that game, they achieved 362 passing yards and 243 rushing yards. Their defense also played well, allowing only six first downs.

Quarterback Brendan Sorsby has been a key player for the Bearcats. He has 1,043 passing yards and 10 passing touchdowns in four games. Wide receiver Cyrus Allen also stands out with 273 receiving yards and five touchdowns this season.

BTB Betting Pick

The Iowa State Cyclones are set to cover the spread of +1.5 (-110) against the Cincinnati Bearcats. Both teams have scored 158 points this season, but Iowa State’s defense shows strength with 9 sacks and 6 interceptions. This defensive edge may help Iowa State cover the spread with a projected score of 28-24 in their favor.

For the total, the recommendation is to take the under 56.5 (-109). Both teams have defenses ranked in the top 50 for points allowed, with Iowa State allowing 71 points and Cincinnati allowing 74. The projected total score is 52, which is below the current line, suggesting a lower-scoring game than expected.